Posatex ,17,5 ml, Otic Suspension for Dogs

Posatex contains three active substances: orbifloxacin, mometasone furoate monohydrate and posaconazole.
Posatex is a white to off-white suspension of ear drops.
It is available in a 17.5 ml bottle for dogs.
What is Posatex used for?

Posatex is used to treat dogs with acute or recurrent episodes of ear infections (otitis externa).
It is given once a day for seven days. The number of ear drops given depends on the weight of the dog and varies between 2 and 8.
The inside of the ear should be cleaned and dried before treatment.
How does Posatex work?

Ear infections in dogs can be caused by bacteria or fungi. Infections can often cause the ear(s) to become inflamed (red, swollen or itchy). Two of the active substances in Posatex, orbifloxacin and posaconazole, work against the cause of the infection, while the third, mometasone furoate monohydrate, works on inflammation.

Orbifloxacin is an antibiotic that belongs to the group of fluoroquinolones. It works by blocking an enzyme called ‘DNA gyrase’, which is important because it prevents bacteria from making copies of their DNA. By blocking ‘DNA gyrase’, orbifloxacin prevents bacteria from making DNA and proteins and from growing, thus leading to the death of the bacteria.

Posaconazole is an antifungal that belongs to the group of triazoles. It works by preventing the formation of ergosterol, which is an important part of the fungal cell wall. Without ergosterol, the fungus is destroyed or its spread is prevented.

Mometasone furoate monohydrate is a steroid, which is a type of substance that helps to reduce inflammation.