C.T.P. 12 , Chloramphenicol 200 mg, Tylosin tartrate 55 mg, Prednisolone 5 mg, Vitamin B12 0.1 mg

COMPOSITION
1 ml of product contains:
Active substances:
Chloramphenicol …………………………………………………………………..200 mg
Tylosin tartrate ………………………………………………………………………..55 mg
Prednisolone …………………………………………………………………………….5 mg
Vitamin B12 ……………………………………………………………………………0.1 mg
Excipients:
Benzyl alcohol …………………………………………………………………………10 mg
INDICATIONS
C.T.P. 12 is indicated in dogs and cats in the treatment of local and
systemic infections caused by germs sensitive to chloramphenicol
and tylosin:
• infections of the digestive system (enteritis, peritonitis), of the
respiratory system (pneumonia, bronchopneumonia, pleurisy), of the
genitourinary system (metritis, nephritis, cystitis);
• skin and soft tissue infections;
• sepsis, meningitis;
• bacterial infections secondary to viral infections;
• bacterial infections resistant to other antibiotics.
CONTRAINDICATIONS
It is not administered in cases of severe liver or kidney failure, in
newborns during the first days of life.
Do not administer to animals known to be hypersensitive to the
active substances or any of the excipients.
ADVERSE REACTIONS
Rarely, skin reactions may occur at the injection site, which remit
shortly.
TARGET SPECIES
Dogs, cats.
ADMINISTRATION
It is administered deep intramuscularly: 0.5 – 1 ml/10 kg body weight
/day. The duration of the treatment is 3-5 days. In special cases,
on the indication of the veterinarian, it can also be administered
every12 hour. To ensure a correct dosage, the body weight of the
animals must be determined as precisely as possible to a avoid
underdosing.
RECOMMENDATIONS FOR PROPER ADMINISTRATION
Aseptic precautions will be used when administering the product.
SPECIAL WARNINGS FOR EACH TARGET SPECIES
C.T.P. 12 should be administered with caution to the youth of the
target species, as well as to females during pregnancy.
USE DURING PREGNANCY, LACTATION
The product is not administered during the final part of the
pregnancy. Because chloramphenicol was detected in milk in a
proportion of 50% compared to serum concentration, the product
should be administered with caution in the lactation period.
INTERACTIONS WITH OTHER MEDICINAL PRODUCTS OR OTHER
FORMS OF INTERACTION
The following substances may interact with the product: Digitalis
glycosides: chloramphenicol and tylosin reduce the rate of elimination
of digitalis glycosides, which can lead to their accumulation in toxic
concentrations. Erythromycin: Erythromycin and chloramphenicol
compete for the same ribosome and are therefore antagonists .
Phenobarbital, pentobarbital and primidone: Chloramphenicol can
inhibit their hepatic metabolism. Chloramphenicol prolongs the
duration of anesthesia with pentobarbital (120% in dogs and 260%
in cats). Phenobarbital can decrease the plasma concentration of
chloramphenicol.
OVERDOSE
Cats are more sensitive than dogs in case of overdose due to the fact
that in cats the half-life of chloramphenicol is longer. Side effects of
overdose may include: loss of appetite, vomiting, diarrhea.
WITHDRAWAL PERIOD
Not applicable.
STORAGE
Store at temperatures below 25°C. Protect from direct light.

PRESENTATION
Bottles x 100 ml