Colistin sulfate FP 50% , Colistin sulfate 0.5 g/g , 1 x bag 10 g

COMPOSITION
1 g of powder contains:
Active substance:
Colistin sulfate …………………………………………………………………………..0.5 g
(equivalent to 10,000,000 IU)
Excipients:
Lactose monohydrate
INDICATIONS
The product is indicated for calves, lambs, kids, piglets, rabbits, birds
(chickens, turkeys, ducks, geese, pigeons, quails, pheasants, guinea
fowls) in the treatment and metaphylaxis of infectious diseases
caused by non-invasive E.Coli bacteria susceptible to colistin. Before
metaphylactic treatment, the presence of the disease in the herd
must be established.
CONTRAINDICATIONS
Do not use in case of hypersensitivity to the active substance or to
the excipient. Do not administer to horses, especially foals, since
colistin, due to the change in the balance of the gastrointestinal
microflora, could lead to the development of colitis associated with
the administration of antimicrobials (colitis X), usually associated
with Clostridium difficile, which can be lethal.
ADVERSE REACTIONS
If the product is administered to animals with severe renal failure,
and the treatment is prolonged beyond the recommended period
(3–6 days), risk of nephrotoxicity may occur.
TARGET SPECIES
Calves, piglets, lambs, rabbits and birds (chickens, turkeys,
ducks, geese, pigeons, quails, pheasants, guinea fowls).
ADMINISTRATION
It is administered orally, individually or in mass. The product is
administered to calves, lambs, kids, piglets and rabbits diluted
in drinking water, herbal infusion or milk, in a dose of 0.9–1.2 g
powder/100 kg body weight/day (4.5–6 mg colistin sulfate/kg b.w.
respectively 100,000 IU/kg b.w.), for 3–6 days.
In birds (chickens, turkeys, ducks, geese, pigeons, quails, pheasants,
bibilici) it is administered diluted in drinking water, in a dose of 9–12
g powder/100 L/day (4.5–6 mg colistin sulfate/kg b.w. respectively
100,000 IU/kg b.w.), for 3–6 days.
For piglets, it is administered in the drinking water, in the amount
of 140 g powder/1000 l water (5 mg colistin sulfate/ kg b.w.
respectively 100,000 I.U./ kg b.w.), for 5–7 days.
RECOMMENDATIONS FOR PROPER ADMINISTRATION
The product must be well diluted in drinking water to achieve its
even dispersion. During the treatment period the animals must
consume only medicated water. Medicated drinking water must be
freshly prepared, every 24 hours.
To ensure correct dosage, the body weight of the animals must be
accurately determined, whenever possible to avoid underdosing. The
duration of the treatment should not exceed 7 days. The duration of
the treatment should be limited to the minimum time necessary for
treating the disease.
USE DURING PREGNANCY, LACTATION OR IN LAYING PERIOD
It can be used during pregnancy, lactation or during the laying
period.
INTERACTIONS WITH OTHER MEDICINAL PRODUCTS OR OTHER
FORMS OF INTERACTION
Avoid concomitant administration with other medicines containing
bivalent metal ions (e.g. calcium or magnesium salts).
WITHDRAWAL PERIOD
Meat and offal: zero days. Eggs: zero days.
STORAGE
Store at temperatures below 25°C. Protect from light. Store in a dry
place.

PRESENTATION
Bag x 10 g