Bisulfim oral solution, Sulfadiazine 200 mg/ml Trimethoprim 40 mg/ml , 50 ml

COMPOSITION
1 ml of solution contains:
Active substances:
Sulfadiazine …………………………………………………………………………..200 mg
Trimethoprim ………………………………………………………………………….40 mg
Excipients:
Polyethylene glycol 400, sodium hydroxide, distilled water.
INDICATIONS
The product is administered to horses, cattle, sheep, pigs, rabbits
and chickens (replacement youth, broilers) in respiratory,
gastrointestinal, urogenital infections, produced by germs sensitive
to sulfadiazine and trimethoprim. The two active substances work
synergistically ensuring a very good antibacterial spectrum, both
on Gram-negative and Gram-positive bacteria: Streptococcus spp.,
Staphylococcus spp., Corynebacterium spp., E. coli, Pasteurella spp.,
Salmonella spp., Bordetella spp., Klebsiella spp., Proteus spp.. It also
acts effectively on some protozoa (Eimeria spp.).
CONTRAINDICATIONS
Do not administer to animals with severe kidney and liver diseases.
Do not administer in case of hypersensitivity to the active substance
or to any of the excipients.
ADVERSE REACTIONS
Sometimes skin rashes (hives), gastric irritation (anorexia, vomiting),
polyarthritis, keratitis may occur.
TARGET SPECIES
Horses, cattle, sheep, pigs, rabbits, chickens (replacement youth,
broilers).
ADMINISTRATION
The product is administered orally, directly or in drinking water,
for 5 – 7 consecutive days, as follows: Horses, cattle, sheep, pigs:
5 ml product/ 80 – 100 kg body weight /day; Rabbits, chickens
(replacement youth, broilers): 4 ml of product/10 L of drinking water
/day. The treatment can be prolonged in the case of severe infections
until the animal heals.
RECOMMENDATIONS FOR PROPER ADMINISTRATION
In order to ensure proper dosing, correctly assess the weight of the
animals to avoid under- or overdosing. The administration of enough
fluids is recommended to avoid crystalluria.
USE DURING PREGNANCY, LACTATION OR IN LAYING PERIOD
It is not recommended to use during pregnancy and lactation. The
product is not used in birds that produce eggs for consumption
human.
INTERACTIONS WITH OTHER MEDICINAL PRODUCTS OR OTHER
FORMS OF INTERACTION
Avoid simultaneous administration with other sulfonamides.
INCOMPATIBILITIES
The product is incompatible with procaine, procaine benzylpenicillin,
local anesthetics, B vitamins.
WITHDRAWAL PERIOD
Meat and offal: horses – 5 days, cattle, sheep, rabbits – 10 days,
pigs – 8 days, chickens (replacement youth, broilers) – 5 days. Milk:
cattle, sheep – 5 days. It is not authorized for use in laying birds that
produce eggs for human consumption.
STORAGE
Store at temperatures below 25o
C. Do not refrigerate or freeze.
Protect from frost. Keep in the original packaging. Keep the bottle
tightly closed. Protect from light.

PRESENTATION
Bottles x 50 ml