Levavermin 50 mg/ml – oral solution for cattle, sheep, pigs

LEVAVERMIN 50 MG/ML*100 ML

Oral solution for cattle, sheep, pigs and broilers.

Levamisole.

STATEMENT OF ACTIVE SUBSTANCES AND OTHER INGREDIENTS
Each ml. of product contains:

Active substance:
Levamisole (as levamisole hydrochloride) 50 mg.

Excipients:
Methylparaben 0.5 mg;
Sodium metabisulfite 0.5 mg.

INDICATIONS
LEVAVERMIN 50 mg/ml is recommended for the treatment of endoparasites.

Cattle and sheep:
Gastrointestinal nematodes:
Trichostrongylus spp,
Cooperia spp,
Ostertagia ostertagi,
Haemonchus spp,
Nematodirus spp,
Bunostomum spp,
Oesophagostomum spp,
Chabertia ovina (mouton).

Lungworms:
Dictyo-caulus viviparus.

Pigs:
Gastrointestinal roundworms:
Ascaris suum;
Strongyloides ransomi;
Oesophagostomum spp.

Lungworms:
Metastrongylus spp.

Broilers:
Ascaridia spp.
Heterakis spp.
Capilaria spp.

CONTRAINDICATIONS
Do not use in case of hypersensitivity to the active substance or to any of the excipients.
Do not use if resistance to levamisole is suspected.

ADVERSE REACTIONS
Sometimes the following may occur: salivation, diarrhea, agitation and tremors.

TARGET SPECIES
Cattle, sheep, pigs and broilers.

DOSAGE FOR EACH SPECIES, ROUTE (RO) OF ADMINISTRATION METHOD
Oral administration.

Dosage:
In cattle and sheep:
7.5 mg levamisole/kg body weight, single administration, without exceeding the total dose of 3.75 g levamisole in cattle 0.375 g levamisole in sheep (0.15 ml product per kg body weight, without exceeding the dose of 75 ml in cattle 7.5 ml in sheep).

Pigs: 7.5 mg levamisole/kg body weight, single administration, without exceeding the total dose of 0.75 g levamisole per animal (0.15 ml product per kg body weight, without exceeding the dose of 15 ml).

Broilers: 20 mg levamisole/kg body weight, approximately 4 ml per litre of drinking water. To ensure correct dosage, the body weight of the animals should be accurately determined, whenever possible, to avoid underdosing.

ADVICE ON CORRECT ADMINISTRATION
Do not use the product if you notice visible signs of damage to the primary packaging.

WITHDRAWAL PERIOD
Meat and offal: 3 days.
Not authorised for use in animals producing milk for human consumption.

SPECIAL STORAGE PRECAUTIONS
Do not store above 25°C.
Do not refrigerate or freeze.
Store in the original packaging.
Store in a dry place.
Protect from direct light.
Do not use after the expiry date stated on the label.
Shelf life after first opening the primary packaging: 28 days.
Shelf life after dilution in drinking water: 24 hours.

SPECIAL WARNING(S)
Special warnings for each target species.
Certain precautions should be taken to avoid the following practices, which may increase the risk of resistance development, leading to ineffective treatment:
– Frequent and repeated use of anthelmintics from the same class over a prolonged period of time.
– Underdosing, which may be due to underestimation of body weight, incorrect administration of the product or failure to calibrate the dosing device (if one exists).

All clinical cases suspected of anthelmintic resistance should be further investigated using appropriate tests (e.g. OPG). Where tests clearly suggest resistance to a particular anthelmintic, another one belonging to a different pharmacological class with a different mode of action should be used.

Special precautions for use in animals:
Not applicable.

Special precautions to be taken by the person administering the veterinary medicinal product to animals:
Avoid direct skin contact. Wash hands after use.
When handling the product, wear appropriate protective clothing, including waterproof rubber gloves.
In case of accidental ingestion, seek medical advice immediately.
People with known hypersensitivity to levamisole should avoid contact with the veterinary medicinal product.

Use during pregnancy, lactation or lay.
Studies on laboratory animals have not revealed a potential teratogenic effect.
Studies on cattle, sheep and pigs have not revealed an embryotoxic or teratogenic potential.
The product can be used during lactation and pregnancy.

Overdose (symptoms, emergency procedures, antidotes), as appropriate
In case of overdose, the signs observed are those resulting from stimulation of the parasympathetic nervous system: salivation, vomiting, diarrhea, rapid breathing and ataxia, tremors, convulsions. The antidotes used are atropine or glycopyrrolate.

Incompatibilities
In the absence of compatibility studies, this veterinary medicinal product should not be mixed with other veterinary medicinal products.

PRECAUTIONS

SPECIAL INSTRUCTIONS FOR DISPOSAL OF UNUSED PRODUCTS OR WASTE MATERIALS, IF ANY
Medicines should not be disposed of via wastewater or household waste.
Ask your veterinarian for information on how to dispose of medicines no longer required. These measures help to protect the environment. Treated animals should be kept in shelters for the entire period of treatment, and the resulting droppings should not be used for soil fertilization.

Packaging presentation:
100 ml bottles.