Parakill 5 ml, External Antiparasitic for Dogs and Cats

ACTIVE INGREDIENTS:

Fipronil 200 mg/ml.

Excipients: ethyl alcohol, tween 80, PVPK 30 and propylene glycol.

INDICATIONS:

It is recommended for the prevention and control of external parasites (ticks, fleas, lice) in dogs and cats.

Ticks – Ixodes ricinus, Rhipicephalus sanguineus, Ripicephalus bursa, Dermacentor marginatus, D. reticulatus, Haemophysalis punctata.

Fleas – Ctenocephalides canic, C. felis, Pulex irritans.

Lice – Trichodectes canis, Felicola subrostrata.

CONTRAINDICATIONS:

Do not administer to animals younger than 6 weeks old, weak, old or allergic to the drug.

ADVERSE REACTIONS:

Profuse salivation may occur, which resolves shortly.

Among the rare adverse reactions to the product may occur: transient skin reactions at the site of application, skin discoloration, local alopecia, pruritus, erythema or generalized pruritus and alopecia.

TARGET SPECIES: dogs and cats.

DOSAGES FOR EACH SPECIES, ROUTE AND METHOD OF ADMINISTRATION:

Administration: topical, “spot on”.

The dose used is: 1- 2 drops/1 kg of live weight. The product is applied to the neck of the animal, in the area where it cannot be licked. It is active for about 4 weeks. Repeating the treatment is only done if necessary, beyond this interval.

Simultaneously with treating the animal, it is mandatory to deworm the shelter, to prevent reinfestation of the animal with parasites.

RECOMMENDATIONS ON CORRECT ADMINISTRATION:

The product is applied to the skin at the neck of the animal. If the amount of product to be applied is larger, it will be applied in several points in the same area.

WITHDRAWAL TIME: Not applicable.

SPECIAL STORAGE CONDITIONS:

Keep out of reach of children. Store at a temperature below 25ºC, in the original packaging, avoiding contact with heat sources or open flames. Do not use after the expiry date stated on the label.

Shelf life of the veterinary medicinal product after first opening: 120 days.

Shelf life of the veterinary medicinal product as packaged: 2 years

SPECIAL WARNINGS:

Immediately after applying the treatment, the animals will be protected from rain.

Avoid contact with the eyes of the animal and the operator.

Wash hands after using the product.

Do not apply to animals with skin wounds.

In case of accidental ingestion of the product or allergies caused by its contact with the skin, seek medical advice immediately and show the product package leaflet or the label.

People with hypersensitivity to one of the components of the product should avoid contact with it.

Use during pregnancy and lactation: Can be used.

Interactions with other medicinal products and other forms of interaction: None known.

Overdose (symptoms, emergency procedures, antidotes)

In case of acute poisoning, symptomatic therapy and general supportive measures should be initiated.

SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED VETERINARY MEDICINAL PRODUCTS OR WASTE MATERIALS, IF ANY:

Any unused veterinary medicinal product or waste materials derived from the use of such products should be disposed of in accordance with local requirements.

PHARMACODYNAMIC PROPERTIES:

Fipronil is a broad-spectrum insecticide of the phenylpyrazole class that acts as a nerve toxin, penetrating the parasite’s body through the stigmata (sensory organs), but especially through the joints of the limbs where the chitin is thinner. Fipronil blocks synapses in the central nervous system of the parasites, resulting in hyperexcitation of the insect’s nerves and muscles, thus causing their death.

PHARMACOKINETICS PROPERTIES:

Fipronil accumulates in the secretion of the sebaceous glands and in the hair follicles, continuing to act for a longer period of time. After application to the animal’s skin, fipronil spreads throughout the body in approximately 24 hours, by translocation. It has no toxic effect on host animals since it is absorbed through the skin in a small proportion (approximately 16%) and decomposes relatively quickly by hydrolysis. The main route of excretion of fipronil is through feces (75%), and a small portion is also eliminated through urine.