Enroxil 5% Injectable 100ml

ENROXIL

Composition
1 ml solution for injection contains 50 mg enrofloxacin.

Indications
Cattle: diseases of the gastrointestinal and respiratory tract, caused by bacteria and mycoplasmas (enteritis and septicemia caused by E.coli, pasteurellosis, salmonellosis, staphylococci, mycoplasmosis) and secondary infections in viral diseases;
Pigs: respiratory and gastrointestinal tract disorders caused by microorganisms susceptible to enrofloxacin (pasteurellosis, enzootic pneumonia, bacterial bronchopneumonia, salmonellosis, M.M.A. syndrome, atrophic rhinitis); – Dog: bacterial infections including disseminated gastrointestinal, respiratory and genitourinary infections, infected wounds and infections of the external auditory canal.

Dosage and method of administration
Cattle: 5 ml/100 kg body weight 
Calves, sheep, goats: 1 ml/20 kg body weight 
Pigs: 1 ml/20 kg body weight 
Dogs: 1 ml/10 kg body weight 
In recurrent respiratory tract infections and salmonellosis, the doses administered will double; This is 5 mg of enrofloxacin per 1 kg of body weight. In calves, no more than 10 ml should be administered at a single point; In sheep and goats, 5 ml in a single point; In lambs, kids and pigs 2.5 ml in a single point. The administration of the preparation will be repeated every 24 hours.

The duration of treatment in calves, sheep, goats and pigs is 2–3 days, and in salmonellosis 5 days. The duration of treatment in dogs is 5 to 10 days.

Contraindications
It is not administered in case of disturbances in the development of cartilage and/or injury to the musculoskeletal system; It is not administered in case of hypersensitivity to the active substance or resistance to quinolones; Do not administer to horses.

Species
Ruminants, Pigs, Dogs

Action
Enrofloxacin is a chemotherapeutic of the fluoroquinolone group (quinolonic derivative of carboxylic acid). It acts bactericidal at low concentrations compared to most Gram negative, Gram positive bacteria and mycoplasmas. The specific mechanism of action of enrofloxacin consists in interfering with the DNA synthesis in the cell nucleus of the microorganism, also determining the prevention of resistance phenomena. At the same time, it is extremely active against microorganisms resistant to beta–lactam antibiotics, tetracyclines, aminoglycosides and macrolides.It is rapidly absorbed from the site of administration and distributed in tissues where it reaches a level several times higher than the serum concentration, in about 1/2-1 hour after administration. Enrofloxacin is active against: Mycoplasma spp., E.coli, Salmonella spp., Campylobacter spp., Haemophilus spp., Pasteurella spp., Bordetella spp., Erysipelothrix rhusiopathiae, Klebsiella spp., Proteus spp., Vibrio parahaemolyticus, Staphylococcus aureus, Streptococcus spp.(B, C, E) and enterococci.

Waiting time
Meat: 10 days.

Presentation
Vials containing 100 ml solution.