ENROFLOX 10% INJ. 100 mg/ml 100 ML, Enrofloxacin

ENROFLOX INJ 10%, solution for injection for cattle and pigs.

DECLARATION OF ACTIVE SUBSTANCE AND OTHER INGREDIENTS
Each ml of product contains:
Active substance:
Enrofloxacin 100 mg
Excipients: N-butyl alcohol, potassium hydroxide, water for injections.

INDICATIONS:
Cattle: diseases of the gastrointestinal tract and respiratory system, caused by bacteria and Mycoplasma spp. (colibacillosis, colisepticemia, pasteurellosis, salmonellosis, staphylococci, mycoplasmosis) and in secondary infections in viral diseases.
Swine: diseases of the gastrointestinal tract and respiratory system caused by microorganisms sensitive to enrofloxacin (pasteurellosis, enzootic pneumonia, bacterial bronchopneumonia, colibacillosis, colisepticemia, salmonellosis, MMA syndrome, atrophic rhinitis).

CONTRAINDICATIONS:
Do not administer the product in case of known resistance to quinolones.
Do not administer the product in case of cartilage growth disorders and/or during injury to the musculoskeletal system, especially at the level of joints that are overworked from a functional point of view or due to body weight.
Do not use in case of hypersensitivity to the active substance or to any of the excipients.

TARGET SPECIES:
Cattle and pigs.

METHOD OF ADMINISTRATION:
The usual dose for cattle and pigs is 2.5 ml Enroflox 10% per 100 kg body weight (2.5 mg enrofloxacin/kg body weight). In recurrent respiratory tract infections and salmonellosis, the recommended dose is doubled: 5 mg enrofloxacin per 1kg body weight.

The product is administered to cattle s.c., to pigs i.m. Enrofloxacin is administered at the usual sites of administration, for example in pigs in the muscles of the posterior area of the ear. In salmonellosis, treatment begins with the injectable form and continues with the oral form.
The medicine is administered once every 24 hours. The duration of treatment in pigs and cattle is 2–3 days, in salmonellosis 5 days. In MMA syndrome in sows, 1–2 days of treatment are required. If no improvement in clinical signs is observed in the first 2–3 days, additional antibiograms and the possibility of changing antimicrobial therapy should be considered.
Recommendations for correct administration:
The dose applied in a single point will not exceed 5 ml in cattle, 2.5 ml in pigs and 5 ml in sows.
Enrofloxacin is administered at the usual sites of administration, for example in pigs in the muscles of the posterior area of the ear. Do not exceed the recommended dose. Normal precautions should be taken when carrying out treatment under sterile conditions.
To ensure a correct dose, body weight must be determined as accurately as possible to avoid overdose.

WAITING TIME:
Meat and organs:
Pigs: 10 days;
Cattle: 10 days;
Cattle milk: 5 days.

PHARMACOKINETIC PARTICULARITIES:
Enrofloxacin is rapidly absorbed from the injection site and distributes into tissues where it reaches a level several times the serum level, in about 1/2 to 1 hour after administration.

FORM OF PRESENTATION:
Polypropylene bottles of  100 ml and closed with a brombutyl rubber stopper and sealed with an aluminium staple.