COMPOSITION
Each 10 g syringe contains:
Active substances:
Neomycin (as sulfate) ……………………………………………………………100 mg
Tylosin (as tartrate) ……………………………………………………………….250 mg
Prednisolone …………………………………………………………………………..10 mg
Vitamin A palmitate ………………………………………………………….10,000 I.U.
Excipients:
Benzyl alcohol …………………………………………………………………………90 mg
Butylhydroxyanisole ………………………………………………………………1.8 mg
Colloidal silicon dioxide, solid paraffin, liquid paraffin.
INDICATIONS
Treatment of mastitis (mammitis) with clinical expression (acute,
sub-acute and chronic) during lactation, as well as subclinical
mastitis during dry period.
CONTRAINDICATIONS
Treatment of animals allergic to neomycin or tylosin shall be avoided
or those with liver dysfunctions.
ADVERSE REACTIONS
Possible allergic reactions, local or systemic.
TARGET SPECIES
Cattle.
ADMINISTRATION
The product is administered intramammary, after complete milking
and sanitization (washing, disinfection) of the affected mammary
quarter. The dose is 10 g of product (one syringe) / affected quarter
/day. The duration of the treatment is 3-5 days depending on the
clinical evolution of the disease.
RECOMMENDATIONS FOR PROPER ADMINISTRATION
Before intramammary administration of the product, the udder must
be completely milked, and the teats and udder must be washed with
water warm and disinfected. Care should be taken not to touch the
tip of the teats when removing dirt from the udder.
After washing, dry the entire surface carefully and wipe down each
teat with a cotton cloth soaked in an antiseptic solution. Insert the tip
of the syringe into the teat deep enough, but not all the way to avoid
injuring the walls of the galactophorous duct, and the content of the
syringe should be injected into each duct while the teat is held firmly.
After inoculation, gently massage for the proper distribution of the
product within the udder.
USE DURING PREGNANCY, LACTATION
NEOTYL is indicated for the treatment of mastitis in cows in the
lactation period and at rest.
INTERACTIONS WITH OTHER MEDICINAL PRODUCTS OR OTHER
FORMS OF INTERACTION
If allergic phenomena occur, taking into account the possibility
of some cross reactions, the following should be avoided in the
treatment of any subsequent infections: kanamycin, streptomycin
and gentamicin.
OVERDOSE
In case of an overdose, adverse reactions, namely allergic reactions,
may occur on rare occasions.
INCOMPATIBILITIES
The following medicines are incompatible with neomycin:
amphotericin B, ampicillin, disodium carbenicillin, cephalozin
sodium, cephalothin sodium, sodium phosphate, dexamethasone
sodium, methicillin sodium, oxacillin sodium, oxytetracycline HCl,
penicillin G, tetracycline HCl, vitamin B in a complex with vitamin
C. The inactivation of aminoglycoside antibiotics by beta-lactam
antibiotics has also been demonstrated in vitro. Prednisolone is
incompatible with: calcium gluconate, dimenhydrinate, sodium
metrotexate, polymyxin B sulfate, promazine HCl.
The interactions of tylosin tartrate with other medicines are not
known. It has been suggested that it may lower blood levels of
digitalis glycosides.
WITHDRAWAL PERIOD
Meat and offal: 7 days. Milk: 3 days.
STORAGE
Store at a temperature below 25°C. Protect from frost. Protect from
direct light.
PRESENTATION
Syringes x 10 g ointment


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