PEN STREP 100ML – SOLUTION FOR INJECTION.
COMPOSITION:
Per ml. suspension:
Procain Benzylpenicillin 200,000 IU
Dihydrostreptomyycin sulfate 250 mg, equivalent to dihydrostreptomycin base 200 mg.
Sodium methyl parahydroxybenzoate 1.14 mg.
DESCRIPTION:
Procain benzylpenicillin is a penicillin with bactericidal action against numerous Gram-positive bacteria (streptococci, Staphylococci, Corynebacteria spp., Erysipelothrix rhusiopathiae, Clostridia spp., Bacillus anthracis) as well as against Gram-negative cocci, Leptospira canicola, Campylobacter foetus and Actinomyces bovis. Dihydrostreptomycin is an aminoglycoside antibiotic with bactericidal action against Gram-negative bacteria, such as: E. coli, Proteus vulgaris, Brucella spp., Salmonella spp., Shighella spp., Klebsiella spp., Pasteurella spp. and Mycoplasma. The combination of the two antibiotics acts synergistically.
INDICATIONS:
Infections caused by microorganisms sensitive to benzylpenicillin and dihydrostreptomycin such as respiratory, uterine, digestive tract infections, mastitis, osteomyelitis, peritonitis, sepsis, cystitis, which evolve in cattle, pigs, sheep, dogs and cats.
TARGET SPECIES:
Cattle, sheep, pigs, dogs, cats.
CONTRAINDICATIONS:
Hypersensitivity to penicillins or aminoglycosides, in case of renal dysfunctions, hearing disorders or vestibular organs. It is not used in small herbivores such as: rabbits, chinchillas, guinea pigs and is not used in prolonged treatment in pregnant animals to avoid the risk of fetal toxicity.
SIDE EFFECTS:
Prolonged administration of high doses may cause renal, vestibular and/or auditory dysfunction and sometimes hypersensitivity reactions.
DOSAGE AND ADMINISTRATION:
Intramuscular administration:
Cattle, pigs, sheep: 1 ml. per 25 kg. live weight, daily, for 3–5 days.
Dogs and cats: 1 ml. per 10 kg. live weight, daily, for 3-5 days.
In severe cases, the dose can be doubled.
Note: shake before use.
WAITING PERIOD:
Pigs: meat and offal 37 days
Cattle and sheep: meat and offal 30 days
Milk: 3 days
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