COMPOSITION
Active substances: Enrofloxacin 2.5g; Oxytetracycline hydrochloride 5g; Iodoform 5g;
Excipients (paraffin oil, neutral vaseline) up to 100 ml.
PHARMACOLOGICAL ACTION
Metrosept E, due to its components, has a strong antimicrobial action, being effective in combating both bacterial infections and those caused by protozoa.
Enrofloxacin is a broad-spectrum chemotherapeutic agent with antimicrobial action, even on antibiotic-resistant germs.
It is a fluorinated derivative of 4-quinolone (fluoroquinolone) belonging to the latest generation of synthetic quinolones, with a notable bactericidal activity on Gram-positive and Gram-negative germs, mycoplasmas and chlamydia.
Compared to the rest of the quinolone group, enrofloxacin has the lowest toxicity.
Oxytetracycline is a broad-spectrum antibiotic that acts on Gram-positive and Gram-negative germs, as well as on flagellated protozoa.
Iodoform is an excellent deodorant, with a high capacity to penetrate modified tissues, it is antiseptic, analgesic and healing of the vaginal and uterine mucosa.
The product is well tolerated by the genital mucosa, both in the case of acute and chronic diseases.
The suspension easily penetrates all affected areas, even in the presence of pseudomembranes and secretions.
TARGET SPECIES: Cow, sheep, goat, sow.
INDICATIONS
Metrosept E is used for the prevention and treatment of metritis, cervicitis and vaginitis in cows, sheep, goats and sows.
Administered after placental retention and dystocic calving, it prevents the onset of infections.
CONTRAINDICATIONS: None.
ADVERSE REACTIONS: None observed.
METHOD OF ADMINISTRATION
Applied intravaginally or intrauterinely, using the following doses:
30 – 40 ml/cow, 2-3 administrations at 24 hour intervals.
10 – 15 ml/sheep, goat and sow, 2-3 administrations at 24 hour intervals.
WARNINGS
Before administering the product, the affected external genitalia is cleaned with soap and water.
The product is applied intravaginally or intrauterinely using dosing syringes equipped with a polyethylene hose.
A sterile surgical glove is used when administering the product.
The product should be used in accordance with the legal, official and local regulations in force.
Fluoroquinolones should be kept as a reserve and should only be used when the infectious disease has not responded effectively or is expected to respond poorly to other classes of antimicrobial products.
The use of fluoroquinolones should be based on a sensitivity test (antibiogram) whenever possible.
Irrational use of the product, without taking into account the mentioned instructions, may increase the antibiotic resistance of bacteria to fluoroquinolones and decrease the effectiveness of treatment with other quinolones, determined by possible cross-resistance
WITHDRAWAL PERIOD
Meat: 28 days;
In animals for milk production: 7 days from the last treatment.


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